ENA panel (Extractable Nuclear Antigen antibodies)

This test is done to detect a group of autoantibodies directed against specific nuclear proteins, including SSA/Ro, SSB/La, RNP, Sm, Scl-70, and others depending on the panel. It is used to help diagnose and differentiate autoimmune connective tissue diseases such as systemic lupus erythematosus, Sjögren’s syndrome, mixed connective tissue disease, and systemic sclerosis.