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HE-4 (ROMA index)

Accredited Facility E-report Qualified Specialists

This test is done to measure human epididymis protein 4 (HE-4), a biomarker associated with ovarian epithelial cancer. When combined with CA-125, it is used to calculate the ROMA (Risk of Ovarian Malignancy Algorithm) score, which helps estimate the likelihood of ovarian cancer in women with pelvic masses.

  • If an ovarian mass is detected.
  • If assessing risk of ovarian cancer.
  • If evaluating pelvic symptoms or abnormal imaging findings.
  • If a healthcare provider is calculating ROMA score with CA-125.
  • Fasting: Not required.
  • No special preparation is usually needed.
  • Inform your healthcare provider about pregnancy or gynecological conditions.
  • Follow any instructions provided by the laboratory or healthcare provider.
  • HE-4 (ROMA index)
    No labs currently offering this test.