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AQP-4 (Aquaporin-4 antibody)

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AQP-4 (Aquaporin-4 antibody)

Accredited Facility E-report Qualified Specialists

This test is done to detect antibodies against aquaporin-4, a water channel protein found in the central nervous system. These antibodies are strongly associated with neuromyelitis optica spectrum disorder (NMOSD), an autoimmune condition that causes inflammation of the optic nerves and spinal cord. It helps differentiate NMOSD from multiple sclerosis and guides diagnosis and treatment.

  • If there are symptoms such as vision loss, eye pain, or weakness.
  • If transverse myelitis or optic neuritis is suspected.
  • If neuromyelitis optica spectrum disorder is being evaluated.
  • If a healthcare provider needs to differentiate from multiple sclerosis.
  • No fasting is required.
  • No special preparation is usually needed.
  • Inform your healthcare provider about immunosuppressive therapy.
  • Follow any instructions provided by the laboratory or healthcare provider.
    • AQP-4 (Aquaporin-4 antibody)
    No labs currently offering this test.