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ANCA Profile (MPO, PR3, cathepsin, elastase, lactoferrin, BPI antibodies)

Accredited Facility E-report Qualified Specialists

This test is done to detect and characterize a broad panel of anti-neutrophil cytoplasmic antibodies (ANCA). It includes MPO and PR3, which are strongly linked to systemic vasculitis, as well as additional neutrophil-associated antibodies (cathepsin G, elastase, lactoferrin, and bactericidal permeability-increasing protein). These markers help evaluate and differentiate autoimmune inflammatory diseases affecting small blood vessels and multiple organs.

  • If there are symptoms of systemic vasculitis such as fever, fatigue, or weight loss.
  • If there is kidney involvement (blood or protein in urine).
  • If there are respiratory symptoms such as chronic cough or shortness of breath.
  • If a healthcare provider is evaluating complex autoimmune or inflammatory disease. 
  • No fasting is required.
  • No special preparation is usually needed.
  • Inform your healthcare provider about immunosuppressive or steroid medications.
  • Follow any instructions provided by the laboratory or healthcare provider.
  • ANCA Profile (MPO, PR3, cathepsin, elastase, lactoferrin, BPI antibodies)
    No labs currently offering this test.